Starting any new medication comes with questions about side effects. With semaglutide, most side effects are mild and temporary, but it's important to know what to expect.
Common Side Effects
The most frequently reported side effects include:
Tips for Managing Side Effects
1. Start low, go slow. Your doctor will start you on a lower dose and gradually increase it 2. Eat smaller meals. Your appetite will be reduced, so smaller portions feel more comfortable 3. Stay hydrated. Drink plenty of water throughout the day 4. Avoid fatty or heavy foods. Light, balanced meals are easier to tolerate 5. Communicate with your care team. If side effects are bothersome, we can adjust your dose
When to Contact Your Doctor
While most side effects are mild, contact your care team if you experience:
Your Majesta care team is available 24/7 to address any concerns.
All Majesta Health medical content is clinically reviewed before publication by US-licensed physicians affiliated with our clinical infrastructure partner, MD Integrations (MDI). Reviewers hold active state medical licenses, are board-certified in primary care or obesity medicine, and specialize in GLP-1 receptor agonist therapy for chronic weight management. MDI is LegitScript certified and SOC 2 Type II accredited.
- US-licensed physicians affiliated with our clinical partner MD Integrations (LegitScript certified, HIPAA, SOC 2 Type II, ISO certified)
- Board-certified in primary care and obesity medicine
- Active state medical licensure required for every prescribing clinician
- Active DEA registration where applicable (note: GLP-1 medications are not controlled substances)
- Telehealth practice across all 50 US states and DC through the MD Integrations Medical Services Organization
- Dispensing pharmacy partner: Belmar Pharma Solutions (LegitScript certified, NABP accredited, 503A and 503B compounding)